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PAR1激动剂。

PAR1 Agonist.

该肽是PAR1特异性激动剂，已被证明在心肌梗塞的实验模型中产生心脏保护作用。它是血小板聚集和凝血的有效抑制剂，并且在动物模型中被发现是有效的抗血栓形成剂。该肽也是一种有效的血管扩张剂，具有治疗高血压的潜力。

This peptide is a PAR1-specific agonist that has been shown to produce cardioprotective effects in experimental models of myocardial infarction. It is a potent inhibitor of platelet aggregation and coagulation, and was found to be an effective antithrombotic agent in animal models. The peptide is also a potent vasodilator with potential for the treatment of hypertension.

蛋白酶激活受体 - 1（PAR-1 激动剂，酰胺）对应于选择性激活 PAR-1 的系留配体序列。酰胺化 C 端提高生化系统中的稳定性和受体结合。其短长度允许功能测定中的精确控制。研究应用包括信号传导通路剖析、受体激活研究和肽结构 - 活性分析。

Protease-Activated Receptor-1, PAR-1 Agonist, amide corresponds to a tethered ligand sequence that selectively activates PAR-1. The amidated C-terminus improves stability and receptor engagement in biochemical systems. Its short length allows precise control in functional assays. Research applications include signaling pathway dissection, receptor-activation studies, and peptide structure-activity analysis.

蛋白酶激活受体 1 激动剂酰胺对应一段拴系配体序列，可选择性激活蛋白酶激活受体 1。酰胺化 C 端提高生化系统中稳定性与受体结合能力。其短长度可实现功能实验精确控制。研究应用包括信号通路解析、受体激活研究与多肽结构‑活性分析。

Protease-Activated Receptor-1, PAR-1 Agonist, amide corresponds to a tethered ligand sequence that selectively activates PAR-1. The amidated C-terminus improves stability and receptor engagement in biochemical systems. Its short length allows precise control in functional assays. Research applications include signaling pathway dissection, receptor-activation studies, and peptide structure-activity analysis.

TFLLRNPNDK-NH2 是一种凝血酶受体激活肽。这种 PAR-1 激动剂肽可逆地与 PAR-1 结合，模拟凝血酶通过底物蛋白水解裂解而提供的“束缚配体”。与凝血酶一样，它也会导致液体和蛋白质渗透性增加。