该高阳离子肽来源于猪髓细胞,与其他抗菌肽相比,具有典型的两亲性结构。PMAP-23对革兰氏阳性和阴性菌株均有抗菌活性,但对人红细胞溶解无活性。
编号:429680
CAS号:
单字母:H2N-RIIDLLWRVRRPQKPKFVTVWVR-OH
PMAP-23是一种来源于猪骨髓细胞中的抗菌肽,由23个氨基酸组成。
该高阳离子肽来源于猪髓细胞,与其他抗菌肽相比,具有典型的两亲性结构。PMAP-23对革兰氏阳性和阴性菌株均有抗菌活性,但对人红细胞溶解无活性。
This highly cationic peptide was derived from porcine myeloid cells, and forms a typical amphipathic structure compared to other antibacterial peptides. PMAP-23 shows antibacterial activity against Gram positive and negative strains but no human erythrocyte lysis activity.
M. Zanetti, P. Storici, A. Tossi, M. Scocchi, R. Gennaro, J. Biol. Chem. 269 (1994) 78557858. Guerreiro, Catarina IPD, et al. Protein expression and purification 59.1 (2008): 161-168.