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GRGDS由5个氨基酸组成，它是一种M细胞靶向肽，可以特异性地结合M细胞顶端表达的β1整合素。

Gly-Arg-Gly-Asp-Ser (TFA) 是一种五肽，构成了糖蛋白，骨桥蛋白与细胞的结合域。Gly-Arg-Gly-Asp-Ser (TFA) 与整合素整联蛋白受体 (integrin receptor) αvβ3 和 αvβ5 结合，IC50 估算值为 ∼5 和 ∼6.5 μM。

Gly-Arg-Gly-Asp-Ser (TFA) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC50 of ∼5 and ∼6.5 μM.

GRGDS醋酸盐是一种合成的整合素拮抗剂，是来源于纤连蛋白的细胞结合区的细胞结合蛋白结构域。

GRGDS acetate, a synthetic integrin antagonist, is a cell-binding protein domain derived from the cell-binding region of fibronectin.

纤连蛋白是一种细胞外基质蛋白，在细胞粘附，迁移和分化中起关键作用。纤连蛋白亚基由三种类型模块的重复单元组成：I型，II型和III型。纤连蛋白的活性片段是指纤连蛋白III型模块内的小肽序列，已被证明具有有效的生物活性。\纤连蛋白活性片段，也称为细胞结合结构域或RGD结构域，是由氨基酸序列Arg-Gly-Asp（RGD）组成的短肽序列。该肽序列与称为整联蛋白的细胞表面受体相互作用，整联蛋白对于介导细胞粘附，迁移和信号传导很重要。\纤维连接蛋白活性片段已被广泛研究，作为研究细胞粘附和迁移机制的研究工具。它还被用于组织工程应用中，以促进合成生物材料上的细胞附着和增殖。

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.\nThe fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.\nThe fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials.

凝血酶诱导的血小板聚集抑制剂，源自纤连蛋白的细胞结合区。该肽竞争性地抑制成纤维细胞与纤连蛋白的直接结合。

Inhibitor of thrombin-induced platelet aggregation, derived from the cell binding region of fibronectin. This peptide competitively inhibits direct binding of fibroblasts to fibronectin.

靶向多肽可以根据其功能和用途分为不同的类别。在PDC（多肽偶联药物）中，靶向多肽通常被分为细胞穿透肽和细胞靶向肽两大类。

细胞穿透肽：这类多肽能够跨越细胞膜，转运具有生物活性的大分子物质，如多肽、蛋白质、核酸等化学药物，使其顺利进入细胞。一些常见的细胞穿透肽包括Pep-1、Pentratin、PepFact14、Transportan等。

细胞靶向肽：这类多肽的作用主要是引导化学药物或生物活性分子与特定类型的细胞结合，以提高其靶向性和治疗效率。常见的细胞靶向肽包括PEGA、生长激素抑制素类似物、蛙皮素类似物、RGD肽类等。