一种 TLR4 激动剂。 RS 09 在体外 RAW264.7 巨噬细胞中促进 NF-κB 核易位并诱导炎性细胞因子分泌。
编号：200755
CAS号：1449566-36-2
单字母：H2N-APPHALS-OH
RS 09是一种TLR4激动剂。RS 09在体外促进RAW264.7巨噬细胞的NF-κB核转位并诱导炎性细胞因子分泌。RS 09在体内起佐剂的作用；当在小鼠中用X-15-KLH给药时，RS 09增强了X-15特异性抗体血清浓度。
RS 09 is a TLR4 agonist. RS 09 promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS 09 acts as an adjuvant in vivo; RS 09 enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.
RS09 2TFA是一种TLR4激动剂，是一种在体外促进NF-κB核转位并诱导RAW264.7巨噬细胞分泌炎症细胞因子的佐剂。RS09增加了疫苗环境中抗体的产生。
RS09 2TFA, a TLR4 agonist, is an adjuvant that promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. RS09 increases antibody production in the vaccine environment.
Arulkumaran Shanmugam,et al. Synthetic Toll Like receptor-4 (TLR-4) Agonist Peptides as a Novel Class of Adjuvants. PLoS One. 2012;7(2):e30839. : https://pubmed.ncbi.nlm.nih.gov/22363498/
