400-998-5282
专注多肽 服务科研

一种有效的、选择性胃动素拮抗剂,pKd 值为 8.24。ANQ-11125 TFA 在体外阻断 motilide 引起的收缩。
编号:200719
CAS号:
单字母:H2N-FVFIFTYGELQRLQ-OH
ANQ-11125 TFA 是一种有效的、选择性胃动素拮抗剂,pKd 值为 8.24。ANQ-11125 TFA 在体外阻断 motilide 引起的收缩。
ANQ-11125 TFA is a potent and selective antagonist of motilin, with the pKd of 8.24. ANQ-11125 TFA blocks motilide-induced contractions in vitro in the rabbit[1][2].
Depoortere I, et, al. Antagonistic properties of [Phe3,Leu13]porcine motilin. Eur J Pharmacol. 1995 Nov 24; 286(3):241-7. : https://pubmed.ncbi.nlm.nih.gov/8608785/
Peeters TL, et, al. The motilin antagonist ANQ-11125 blocks motilide-induced contractions in vitro in the rabbit. Biochem Biophys Res Commun. 1994 Jan 28; 198(2): 411-6. : https://pubmed.ncbi.nlm.nih.gov/8297350/





