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RVD Hpα是一种N-末端延伸的人类加压素,作为选择性CB1受体激动剂。RVD Hpα增加体外表达CB1受体的细胞内Ca2+水平。RVD Hpα也是高亲和力CB2阳性变构调节剂(Ki=50nM)。
编号:200682
CAS号:1193362-76-3/1431329-51-9
单字母:H2N-RVDPVNFKLLSH-OH
| 溶解度: | Soluble in water |
RVD Hpα是一种N-末端延伸的人类加压素,作为选择性CB1受体激动剂。RVD Hpα增加体外表达CB1受体的细胞内Ca2+水平。RVD Hpα也是高亲和力CB2阳性变构调节剂(Ki=50nM)。
RVD-Hpα is the N-terminally extended form of human hemopressin that acts as a selective CB1 receptor agonist. RVD-Hpα increases intracellular Ca2+ levels in cells expressing CB1 receptors in vitro. RVD-Hpα also high affinity CB2 positive allosteric modulator (Ki=50 nM).
RVD Hpα是一种作为选择性CB1受体激动剂的神经肽。已经证明它可以增加ERK1/2水平的磷酸化或细胞内Ca2+的释放。
RVD-Hpα is a neuropeptide that acts as a selective CB1 receptor agonist. It has been demonstrated to increase the phosphorylation of ERK1/2 levels or release of intracellular Ca2+.





