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由beta淀粉样蛋白的 1 到 20 个氨基酸组成。
编号:200625
CAS号:186319-68-6
单字母:H2N-DAEFRHDSGYEVHHQKLVFF-OH
β-Amyloid (1-20) 由 β-淀粉样蛋白的 1 到 20 个氨基酸组成。
β-Amyloid (1-20) consists of amino acids 1 to 20 of beta amyloid protein[1].
β- 淀粉样蛋白(1-20)包含柔性 N 端和部分中央疏水核心,可揭示早期结构变化。该片段表现出环境依赖性构象转变,可从无规卷曲变为伸展结构,适合进行详细的光谱与热力学表征。研究人员将其用于金属结合、聚集起始分析及多肽工程研究。
Beta-Amyloid (1-20) includes the flexible N-terminus and part of the central hydrophobic core, providing insight into early-stage structural changes. The fragment exhibits environment-dependent conformational transitions, from random coil to extended structures. Its composition allows detailed spectroscopic and thermodynamic characterization. Researchers use it in metal-binding studies, aggregation-initiation analysis, and peptide-engineering projects.
| DOI | 名称 | |
|---|---|---|
| 10.3233/JAD-2011-101938 | Structural and functional alterations in amyloid-β precursor protein induced by amyloid-β peptides | 下载 |





