400-998-5282
专注多肽 服务科研

一种 proSAAS 衍生的神经肽。
编号:200577
CAS号:501036-69-7
单字母:H2N-LENPSPQAPARRLLPP-OH
| 溶解度: | Soluble in water |
BigLEN(mouse) is a GPR171 agonist. BigLEN(mouse) is a proSAAS-derived neuropeptide. BigLEN(mouse) regulates food intake in mice. BigLEN(mouse) inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins.
BigLEN(mouse) is a GPR171 agonist. BigLEN(mouse) is a proSAAS-derived neuropeptide. BigLEN(mouse) regulates food intake in mice. BigLEN(mouse) inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins.
大 LEN 多肽是一种延伸的前体样多肽,整合 LEN 型神经多肽序列元件。其结构适用于评估蛋白水解加工通路和结构域组织。混合残基组成影响折叠倾向和配体接触。研究用途包括神经多肽成熟研究、结构分析和基序表征。
Big LEN encompasses an extended precursor-like peptide integrating sequence elements from LEN-type neuropeptides. Its structure supports evaluation of proteolytic processing pathways and domain organization. The mixed residue composition affects folding tendencies and ligand contacts. Research uses include neuropeptide maturation studies, structural analysis, and motif characterization.
BigLEN(mouse) BigLEN(mouse)是一种有效和选择性的孤儿G蛋白偶联受体171(GPR171)激动剂,Kd 值约为0.5nM。BigLEN(mouse)可用于调节与食物摄入和新陈代谢相关的反应。





