400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
| 编号: | 200433 |
| 中文名称: | Z-Gly-Pro-βNA |
| CAS号: | 67336-99-6 |
| 单字母: | Z-GP-βNA |
| 三字母: | Cbz N端Cbz保护，苄氧羰基（Cbz，Z） -Gly甘氨酸：glycine。系统命名为 2-氨基乙酸。是编码氨基酸中没有旋光性的最简单的氨基酸，因具有甜味而得名。符号：G，Gly。 -ProL-脯氨酸：proline。系统命名为吡咯烷-(2S)-羧酸。为亚氨基酸。是编码氨基酸。在肽链中有特殊作用，如易形成顺式的肽键等。符号：P，Pro。 -βNA2-萘胺 |
| 氨基酸个数: | 2 |
| 分子式: | C25H25O4N3 |
| 平均分子量: | 431.48 |
| 精确分子量: | 431.18 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | - |
| 平均亲水性: | - |
| 疏水性值: | -1 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | CBZ修饰肽 600+种二肽(Dipeptide)现货 |
Specific fluorogenic substrate for prolyl endopeptidase (post-proline cleaving enzyme).
苄氧羰基 - 甘氨酸 - 脯氨酸 -βNA 是一种显色底物，设计用于脯氨酸特异性肽酶。βNA 基团可直接监测催化事件。其结构排布促进选择性识别。该底物用于蛋白酶研究中的动力学和机制研究。
Z-Gly-Pro-βNA is a chromogenic substrate designed for proline-specific peptidases. The βNA group enables direct monitoring of catalytic events. Its structural arrangement promotes selective recognition. The substrate is used in kinetic and mechanistic studies within protease research.
Z-Gly-Pro-βNA检测脯氨酰内肽酶(prolyl endopeptidase)的一个特异性荧光底物。
| DOI | 名称 | |
|---|---|---|
| 10.1007/s11010-013-1778-4 | Structure-activity relationships of αs-casein peptides with multifunctional biological activities | 下载 |
| 10.1074/jbc.M208043200 | Electrostatic effects and binding determinants in the catalysis of prolyl oligopeptidase. Site specific mutagenesis at the oxyanion binding site | 下载 |
| 10.1074/jbc.M207386200 | Substrate-dependent competency of the catalytic triad of prolyl oligopeptidase | 下载 |
| 10.1016/s0041-0101(02)00180-0 | Fluorometric assay using naphthylamide substrates for assessing novel venom peptidase activities | 下载 |
| 10.1111/j.1432-1033.2004.04127.x | A Kazal prolyl endopeptidase inhibitor isolated from the skin of Phyllomedusa sauvagii | 下载 |
| 10.1016/j.jmb.2004.05.011 | Concerted structural changes in the peptidase and the propeller domains of prolyl oligopeptidase are required for substrate binding | 下载 |
| 10.1128/jb.174.8.2454-2459.1992 | Proline-specific endopeptidases from microbial sources: isolation of an enzyme from a Xanthomonas sp | 下载 |
| 10.1016/j.bcp.2005.03.002 | Representative aminopeptidases and prolyl endopeptidase from murine macrophages: comparative activity levels in resident and elicited cells | 下载 |
| 10.1016/j.mcn.2004.12.003 | How can the mood stabilizer VPA limit both mania and depression? | 下载 |
| 10.1016/j.chembiol.2005.05.016 | Determination of intracellular prolyl/glycyl proteases in intact living human cells and protoporphyrin IX production as a reporter system | 下载 |
| 10.1155/2008/794050 | Methotrexate and cyclosporine treatments modify the activities of dipeptidyl peptidase IV and prolyl oligopeptidase in murine macrophages | 下载 |
| 10.1530/REP-08-0192 | Peptidase activities in Crotalus durissus terrificus semen | 下载 |
| 10.1016/j.ygcen.2008.10.022 | Seasonal variation of peptidase activities in the reproductive tract of Crotalus durissus terrificus | 下载 |
| 10.1016/0005-2744(79)90053-6 | Post-proline cleaving enzyme. Synthesis of a new fluorogenic substrate and distribution of the endopeptidase in rat tissues and body fluids of man | 下载 |
| 10.1016/0014-5793(80)80782-4 | Specific fluorogenic substrates for the TRF-deamidating post proline cleaving enzyme | 下载 |
| 10.1093/oxfordjournals.jbchem.a133477 | Post-proline cleaving enzyme from lamb brain | 下载 |
| 10.1074/jbc.M007003200 | Structures of prolyl oligopeptidase substrate/inhibitor complexes. Use of inhibitor binding for titration of the catalytic histidine residue | 下载 |
