400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
Z-RR-βNA，对组织蛋白酶 B 具有最大灵敏度的特异性底物，不受组织蛋白酶 H 的干扰。该底物的储备液最好在 DMSO 中制备。
编号：200417
CAS号：76474-52-7
单字母：Z-RR-βNA
| 编号: | 200417 |
| 中文名称: | Z-Arg-Arg-βNA |
| CAS号: | 76474-52-7 |
| 单字母: | Z-RR-βNA |
| 三字母: | Cbz N端Cbz保护，苄氧羰基（Cbz，Z） -ArgL-精氨酸：arginine。系统命名为(2S)-氨基-5-胍基戊酸。在生理条件下带正电荷，为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号：R，Arg。 -ArgL-精氨酸：arginine。系统命名为(2S)-氨基-5-胍基戊酸。在生理条件下带正电荷，为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号：R，Arg。 -βNA2-萘胺 |
| 氨基酸个数: | 2 |
| 分子式: | C30H39O4N9 |
| 平均分子量: | 589.69 |
| 精确分子量: | 589.31 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 2 |
| 平均亲水性: | 3 |
| 疏水性值: | -4.5 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | CBZ修饰肽 600+种二肽(Dipeptide)现货 |
Z-RR-βNA, specific substrate of maximal sensitivity for cathepsin B, free from interference by cathepsin H. Stock solutions of this substrate are best prepared in DMSO.
Z-Arg-Arg-βNA 别名 Z-RR-βNA，是组织蛋白酶 B(cathepsin B)最大敏感度的一个特异性底物，可以摆脱组织蛋白酶 H(cathepsin H)的干扰。溶液保存Z-Arg-Arg-βNA的时候最好使用DMSO溶液。
| DOI | 名称 | |
|---|---|---|
| 10.1042/bj2270521 | A general framework of cysteine-proteinase mechanism deduced from studies on enzymes with structurally different analogous catalytic-site residues Asp-158 and -161 (papain and actinidin), Gly-196 (cathepsin B) and Asn-165 (cathepsin H). Kinetic studies up to pH 8 of the hydrolysis of N-alpha-benzyloxycarbonyl-L-arginyl-L-arginine 2-naphthylamide catalysed by cathepsin B and of L-arginine 2-naphthylamide catalysed by cathepsin H | 下载 |
| 10.1042/bj2270511 | Preparation of cathepsins B and H by covalent chromatography and characterization of their catalytic sites by reaction with a thiol-specific two-protonic-state reactivity probe. Kinetic study of cathepsins B and H extending into alkaline media and a rapid spectroscopic titration of cathepsin H at pH 3-4 | 下载 |
| 10.1016/0024-3205(75)90137-x | On the substrate specificity of cathepsins B1 and B2 including a new fluorogenic substrate for cathepsin B1 | 下载 |
| 10.1042/bj2010367 | Action of rat liver cathepsin L on collagen and other substrates | 下载 |
| 10.1042/bj1890447 | Human cathepsin B. Application of the substrate N-benzyloxycarbonyl-L-arginyl-L-arginine 2-naphthylamide to a study of the inhibition by leupeptin | 下载 |
| 10.1016/0003-2697(76)90298-0 | An improved color reagent for use in Barrett's assay of Cathepsin B | 下载 |
