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AQEE-30 (VGF588-617) 是一种 Pro-VGF 衍生肽,可增加海马神经元的突触电荷,注射到雄性大鼠的室旁核时诱导阴茎勃起,鞘内注射到幼稚成年小鼠时引起热痛觉过敏。
编号:200061
CAS号:323185-80-4
单字母:H2N-AQEEADAEERRLQEQEELENYIEHVLLHRP-OH
| 溶解度: | Soluble in water |
AQEE-30 (VGF588-617) is a Pro-VGF-derived peptide that increases synaptic charge in hippocampal neurons, induces penile erection when injected into the paraventricular nucleus of male rats and evokes thermal hyperalgesia when injected intrathecally into naïve adult mice.
AQEE-30(小鼠、大鼠)是一种保守神经肽,用于跨物种研究折叠、受体相互作用与结构基序。其两亲性序列支持构象与生物物理建模。该肽有助于定位神经肽系统中的最小决定因素。应用包括配体设计与肽 - 蛋白相互作用研究。
AQEE-30 (mouse, rat) is a conserved neuropeptide used to study folding, receptor interactions, and structural motifs across species. Its amphipathic sequence supports conformational and biophysical modeling. The peptide aids in mapping minimal determinants in neuropeptide systems. Applications include ligand design and peptide-protein interaction studies.
| DOI | 名称 | |
|---|---|---|
| 10.1523/JNEUROSCI.23-34-10800.2003 | Brain-derived neurotrophic factor-induced gene expression reveals novel actions of VGF in hippocampal synaptic plasticity | 下载 |
| 10.1111/j.1460-9568.2004.03781.x | Pro-VGF-derived peptides induce penile erection in male rats: possible involvement of oxytocin | 下载 |
| 10.1016/j.neuropharm.2005.05.015 | Pro-VGF-derived peptides induce penile erection in male rats: Involvement of paraventricular nitric oxide | 下载 |
| 10.1523/JNEUROSCI.1127-09.2009 | Proteomic analysis uncovers novel actions of the neurosecretory protein VGF in nociceptive processing | 下载 |
| 10.1016/j.celrep.2016.09.030 | Voluntary Running Triggers VGF-Mediated Oligodendrogenesis to Prolong the Lifespan of Snf2h-Null Ataxic Mice | 下载 |





