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编号: | 179331 |
中文名称: | 标记肽Boc-QAR-对硝基苯胺 |
英文名: | Boc-Gln-Ala-Arg-pNA |
CAS号: | 1926163-47-4 |
单字母: | Boc-QAR-pNA |
三字母: | Boc N端Boc保护;叔丁氧羰基或叔丁氧羰基(Boc)是胺的保护基团。Boc基团可用强酸去除,如用三氟乙酸在二氯甲烷中去除,或用HCl在甲醇中去除。 -GlnL-谷氨酰胺:glutamine。系统命名为(2S)-氨基-4-氨酰基丁酸,是编码氨基酸。符号:GIn,Q。 -Ala丙氨酸:alanine。L-丙氨酸的系统命名为(2S)-氨基丙酸,是编码氨基酸,也叫L-α-丙氨酸。符号:A,Ala。D-丙氨酸存在于多种细菌细胞壁的糖肽中。β-丙氨酸是维生素泛酸和辅酶A的组分。 -ArgL-精氨酸:arginine。系统命名为(2S)-氨基-5-胍基戊酸。在生理条件下带正电荷,为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号:R,Arg。 -pNA对硝基苯胺 |
氨基酸个数: | 3 |
分子式: | C25H39O8N9 |
平均分子量: | 593.63 |
精确分子量: | 593.29 |
等电点(PI): | - |
pH=7.0时的净电荷数: | 1 |
平均亲水性: | 0.9 |
疏水性值: | -2.07 |
消光系数: | - |
来源: | 人工化学合成,仅限科学研究使用,不得用于人体。 |
盐体系: | 可选TFA、HAc、HCl或其它 |
储存条件: | 负80℃至负20℃ |
标签: | pNA修饰肽 三肽 |
Boc-QAR-pNA, chromogenic substrate for trypsin and matriptase-2.
Boc-Gln-Ala-Arg-pNA hydrochloride salt is a reagent, speciality chemical, and useful building block. It is used as a reaction component in the synthesis of complex compounds. Boc-Gln-Ala-Arg-pNA hydrochloride salt can be used as a versatile building block for the construction of new scaffolds. The high purity and quality of this compound make it an excellent choice for research chemicals and other fine chemicals.
DOI | 名称 | |
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10.1074/jbc.M803041200 | Activation mechanism of recombinant Der p 3 allergen zymogen: contribution of cysteine protease Der p 1 and effect of propeptide glycosylation | 下载 |
10.1042/BJ20091565 | Proteolytic processing of the serine protease matriptase-2: identification of the cleavage sites required for its autocatalytic release from the cell surface | 下载 |
10.1021/jm100183e | Identification of the first low-molecular-weight inhibitors of matriptase-2 | 下载 |
10.1182/blood-2011-04-348698 | Regulation of TMPRSS6 by BMP6 and iron in human cells and mice | 下载 |
10.1002/anie.201108983 | Braces for the peptide backbone: insights into structure-activity relationships of protease inhibitor mimics with locked amide conformations | 下载 |
10.1002/cbic.201200604 | Oxidative folding of peptides with cystine-knot architectures: kinetic studies and optimization of folding conditions | 下载 |
10.1042/BJ20121518 | Hepatocyte growth factor activator inhibitor type 2 (HAI-2) modulates hepcidin expression by inhibiting the cell surface protease matriptase-2 | 下载 |
10.1074/jbc.M112.449033 | Mutational tail loss is an evolutionary mechanism for liberating marapsins and other type I serine proteases from transmembrane anchors | 下载 |
10.1016/j.bbagen.2013.11.017 | Der p 1 is the primary activator of Der p 3, Der p 6 and Der p 9 the proteolytic allergens produced by the house dust mite Dermatophagoides pteronyssinus | 下载 |
10.1002/anie.201404668 | Effective PHIP labeling of bioactive peptides boosts the intensity of the NMR signal | 下载 |