从发酵乳中分离的降压肽对血管紧张素 I 转换酶 (ACE) 的抑制活性较低，IC₅ ₀ 720 μM。二肽可能是内吗啡肽的生物合成前体。
编号：189137
CAS号：51871-47-7
单字母：H2N-YP-OH
| 编号: | 189137 |
| 中文名称: | 二肽alpha-Casomorphin(1-2) |
| 英文名: | alpha-Casomorphin(1-2) |
| CAS号: | 51871-47-7 |
| 单字母: | H2N-YP-OH |
| 三字母: | H2N N端氨基 -Tyr酪氨酸 -Pro脯氨酸 -OHC端羧基 |
| 氨基酸个数: | 2 |
| 分子式: | C14H18N2O4 |
| 平均分子量: | 278.3 |
| 精确分子量: | 278.13 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 1.97 |
| 平均亲水性: | -3.4 |
| 疏水性值: | -1.25 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | 1490 |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 二肽(Dipeptide) |
The antihypertensive peptide isolated from fermented milk had a low inhibitory activity against angiotensin I-converting enzyme (ACE), IC₅ ₀ 720 μM. The dipeptide is a possible biosynthetic precursor of endomorphin.
| DOI | 名称 | |
|---|---|---|
| 10.3168/jds.S0022-0302(99)75364-6 | Purification and characterization of an antihypertensive peptide from a yogurt-like product fermented by Lactobacillus helveticus CPN4 | 下载 |
| 10.1021/ja0164327 | Spectroscopic properties of tyrosyl radicals in dipeptides | 下载 |
| 10.1016/j.regpep.2005.12.004 | Endomorphin synthesis in rat brain from intracerebroventricularly injected [3H]-Tyr-Pro: a possible biosynthetic route for endomorphins | 下载 |
| 10.1021/jp303607b | Redox-induced conformational switching in photosystem-II-inspired biomimetic peptides: a UV resonance Raman study | 下载 |
| 10.1016/j.foodchem.2012.02.183 | Production of dipeptidyl peptidase IV inhibitory peptides from defatted rice bran | 下载 |
