作为色氨酸和二肽 Val-Trp (N-1170)，Trp-Val 被证明是一种有效的非竞争性黄嘌呤氧化酶抑制剂。与反向二肽相反，Trp-Val 还抑制 DPP IV。
编号：137504
CAS号：24613-12-5
单字母：H2N-WV-OH
| 编号: | 137504 |
| 中文名称: | 二肽Trp-Val |
| 英文名: | Trp-Val |
| CAS号: | 24613-12-5 |
| 单字母: | H2N-WV-OH |
| 三字母: | H2N N端氨基 -Trp色氨酸 -Val缬氨酸 -OHC端羧基 |
| 氨基酸个数: | 2 |
| 分子式: | C16H21N3O3 |
| 平均分子量: | 303.36 |
| 精确分子量: | 303.16 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 0.97 |
| 平均亲水性: | -2.45 |
| 疏水性值: | 1.65 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | 5500 |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 二肽(Dipeptide) |
As tryptophan and the dipeptide Val-Trp (N-1170), Trp-Val, and was shown to be an effective non-competitive inhibitor of xanthine oxidase. Trp-Val also inhibited DPP IV, contrary to the inverse dipeptide.
| DOI | 名称 | |
|---|---|---|
| 10.1016/j.peptides.2012.07.030 | Tryptophan-containing milk protein-derived dipeptides inhibit xanthine oxidase | 下载 |
| 10.1016/j.peptides.2012.11.016 | Dipeptidyl peptidase IV inhibitory and antioxidative properties of milk protein-derived dipeptides and hydrolysates | 下载 |
| 10.1016/j.foodchem.2014.06.059 | Tryptophan-containing dipeptides are C-domain selective inhibitors of angiotensin converting enzyme | 下载 |
