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来自人脑的淀粉样前体蛋白（APP）β-分泌酶在淀粉样蛋白（Aβ）序列的氨基末端切割全长APP，从而导致β-切割的可溶性APP和相应的细胞相关羧基末端片段的产生和细胞外释放。随后γ-分泌酶对C端片段的切割导致Aβ的形成。这种新肽代表了具有IC的APPβ-分泌酶的有效底物类似物抑制剂₅₀ = 30 nM.

Amyloid precursor protein (APP) β-secretase from human brain cleaves full-length APP at the amino terminus of the amyloid β-protein (Aβ) sequence, thus leading to the generation and extracellular release of β-cleaved soluble APP and a corresponding cell-associated carboxy-terminal fragment. The subsequent cleavage of the C-terminal fragment by γ-secretase(s) leads to the formation of Aβ. This new peptide represents a potent substrate analog inhibitor of APP β-secretase with IC₅₀ = 30 nM.

Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe是一种抑制β2肾上腺素能受体与其配体之间相互作用的肽。它是一种高纯度的β2肾上腺素能受体非肽抑制剂，可用于研究目的。Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe抗体可用于在蛋白质印迹或ELISA实验中鉴定该肽。

Lys-Thr-Glu-Glu-Ile-Ser-Glu-Val-Asn-Sta-Val-Ala-Glu-Phe is a peptide that inhibits the interaction between the beta2 adrenergic receptor and its ligand. It is a high purity, nonpeptide inhibitor of the beta2 adrenergic receptor that is useful for research purposes. The antibody to Lys-Thr-Glu-Glu-Ile-Ser-Glu Val Asn Sta Val Ala Glu Phe can be used to identify this peptide in Western blot or ELISA experiments.

这种基于 statine 的底物类似物 β 分泌酶抑制剂 P10–P4’ statV，用于抑制野生型小鼠皮质匀浆和从人脑中纯化的 BACE 的 β 分泌酶活性。

This statine-based substrate analog, ?-secretase inhibitor P10–P4’ statV, is used in the inhibition of ?-secretase activity from homogenized wild-type mouse cortices and from BACE-purified from human brain.