400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
| 编号: | 110647 |
| 中文名称: | 二肽L-Gly-L-Pro |
| 中文同义词: | 甘氨酸-L-脯氨酸 |
| 英文名: | Gly-Pro |
| 英文同义词: | Glycyl-glycyl-L-proline |
| CAS号: | 704-15-4 |
| 单字母: | H2N-GP-OH |
| 三字母: | H2N N端氨基：N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时，通常将N端放在肽链的左边。 -Gly甘氨酸：glycine。系统命名为 2-氨基乙酸。是编码氨基酸中没有旋光性的最简单的氨基酸，因具有甜味而得名。符号：G，Gly。 -ProL-脯氨酸：proline。系统命名为吡咯烷-(2S)-羧酸。为亚氨基酸。是编码氨基酸。在肽链中有特殊作用，如易形成顺式的肽键等。符号：P，Pro。 -OHC端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。 |
| 氨基酸个数: | 2 |
| 分子式: | C7H12N2O3 |
| 平均分子量: | 172.18 |
| 精确分子量: | 172.08 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 0.97 |
| 平均亲水性: | - |
| 疏水性值: | -1 |
| 外观与性状: | 白色粉末状固体 |
| 沸点: | 411.3°Cat760mmHg |
| 熔点: | 185°C |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 600+种二肽(Dipeptide)现货 |
| MDL号: | MFCD00020840 |
| 参考文献（References）: | <ALLPEPTIDE>Le J, et al. Urine glycyl-L-proline increase and skin trophicity. Amino Acids. 1999;17(3):315-22.<ALLPEPTIDE>Anna Walter, et al. Glycerophosphocholine is elevated in cerebrospinal fluid of Alzheimer patients. Neurobiol Aging. 2004 Nov-Dec;25(10):1299-303.<ALLPEPTIDE>H U Shetty, et al. Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease. Clin Chem. 1996 Feb;42(2):298-302.<ALLPEPTIDE>Hans F N Kvitvang, et al. Highly sensitive GC/MS/MS method for quantitation of amino and nonamino organic acids. Anal Chem. 2011 Apr 1;83(7):2705-11.<ALLPEPTIDE>J D Shoemaker, et al. Automated screening of urine samples for carbohydrates, organic and amino acids after treatment with urease. J Chromatogr. 1991 Jan 2;562(1-2):125-38. |
| TPSA: | 83.63 |
| LogP : | -0.9793 |
| H_Acceptors: | 3.0 |
| H_Donors: | 2.0 |
| Rotatable_Bonds: | 2.0 |
| 警示词: | Warning |
| 危险申明: | H302-H315-H319-H335 |
| 警告申明: | P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501 |
| GHS编码: | GHS07 |
| SMILES: | NCC(N1CCC[C@H]1C(O)=O)=O |
H-Gly-Pro-OH 是胶原蛋白代谢的最终产物，它会进一步被脯氨肽酶进一步裂解。
H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.
Gly-Pro is a cyclic peptide that binds to DPP-IV and inhibits proteolytic activity. It has been shown to have inhibitory properties against infectious diseases and cancer tissues, as well as a fluorescence probe for the detection of DPP-IV. Gly-Pro is also a potential inhibitor of neuronal death and has been shown to have structural analysis in the form of molecular docking analysis.
H-Gly-Pro-OH H-Gly-Pro-OH 是胶原蛋白代谢的最终产物，它会进一步被脯氨肽酶进一步裂解。
H-Gly-Pro-OH是胶原蛋白代谢的最终产物，能够被脯氨肽酶进一步裂解。
| DOI | 名称 | |
|---|---|---|
| 10.1002/jps.10325 | Extracellular glucose concentration alters functional activity of the intestinal oligopeptide transporter (PepT-1) in Caco-2 cells | 下载 |
| 10.1007/BF01366930 | Urine glycyl-L-proline increase and skin trophicity | 下载 |
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