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H-Gly-Pro-OH 是胶原蛋白代谢的最终产物，它会进一步被脯氨肽酶进一步裂解。
H-Gly-Pro-OH is an end product of collagen metabolism that is further cleaved by prolidase.

Peptide H-GP-OH is a Research Peptide with significant interest within the field academic and medical research. Recent citations using H-GP-OH include the following: Gaussian process: a promising approach for the modeling and prediction of peptide binding affinity to MHC proteins Y Ren, X Chen, M Feng, Q Wang - Protein and peptide , 2011 - ingentaconnect.comhttps://www.ingentaconnect.com/content/ben/ppl/2011/00000018/00000007/art00004 Characterization of the binding profile of peptide to transporter associated with antigen processing (TAP) using Gaussian process regression Y Ren, B Wu, Y Pan, F Lv, X Kong, X Luo, Y Li - Computers in biology , 2011 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0010482511001521 Delta-peptide is the carboxy-terminal cleavage fragment of the nonstructural small glycoprotein sGP of Ebola virus VA Volchkova, HD Klenk, VE Volchkov - Virology, 1999 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S004268229990034X A defined peptide that inhibits the formation of the glycoprotein IIb and IIIa complex TM Chiang, J Zhu - Thrombosis research, 2005 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0049384804005924 Triflavin, an antiplatelet Arg-Gly-Asp-containing peptide, is a specific antagonist of platelet membrane glycoprotein IIb-IIIa complex TF Huang, JR Sheu, CM Teng - The Journal of , 1991 - academic.oup.comhttps://academic.oup.com/jb/article-abstract/109/2/328/1032286 Evaluation of interaction forces between profilin and designed peptide probes by atomic force microscopy T Okada, M Sano, Y Yamamoto, H Muramatsu - Langmuir, 2008 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/la703344u Identification of Lassa virus glycoprotein signal peptide as a trans-acting maturation factor R Eichler, O Lenz, T Strecker, M Eickmann - EMBO , 2003 - embopress.orghttps://www.embopress.org/doi/abs/10.1038/sj.embor.7400002 Modeling and prediction of binding affinities between the human amphiphysin SH3 domain and its peptide ligands using genetic algorithm-Gaussian processes P Zhou , F Tian, X Chen, Z Shang - Peptide Science, 2008 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/bip.21091 Binding peptide-promoted biofunctionalization of graphene paper with hydroxyapatite for stimulating osteogenic differentiation of mesenchymal stem cells M Wang, T Yang , Q Bao , M Yang - ACS Applied Materials & , 2021 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acsami.1c20740 Immuno-affinity purification of specific antibodies against human gastrin releasing peptide (h-GRP) by the h-GRP (1-8)-linked poly dimethylacrylamide resin M TAKEYAMA, T KINO, L GUO - Journal of Peptide , 1989 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/j.1399-3011.1989.tb00223.x Synthesis, evaluation and Tc-99m complexation of a hydrazinonicotinyl conjugate of a GP IIb/IIIa antagonist cyclic peptide for the detection of deep vein thrombosis M Rajopadhye, TD Harris, K Yu, D Glowacka - Bioorganic & Medicinal , 1997 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0960894X97000838 Proline-containing peptides-New insight and implications: A Review M Misiura, W Miltyk - Biofactors, 2019 - Wiley Online Libraryhttps://iubmb.onlinelibrary.wiley.com/doi/abs/10.1002/biof.1554 Dipeptidyl peptidase IV inhibitory peptides generated in Spanish dry-cured ham M Gallego, MC Aristoy, F Toldra - Meat science, 2014 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0309174013005329 Synthetic peptides derived from fibrinogen and fibronectin change the conformation of purified platelet glycoprotein IIb-IIIa. LV Parise, SL Helgerson, B Steiner, L Nannizzi - Journal of Biological , 1987 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0021925818452477 Triflavin, an Arg-Gly-Asp-containing Peptide, Inhibits Tumor Cell-induced Platelet Aggregation JR Sheu, CH Lin, HC Peng, CM Teng - Japanese journal of , 1993 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1111/j.1349-7006.1993.tb02802.x Complex of a protective antibody with its ebola virus GP peptide epitope: Unusual features of a VÃ\x8e»x light chain JE Lee, A Kuehne, DM Abelson, ML Fusco - Journal of molecular , 2008 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0022283607013393 Arginine-glycine-aspartic acid-and fibrinogen gamma-chain carboxyterminal peptides inhibit platelet adherence to arterial subendothelium at high wall shear rates. An JB Lawrence, WS Kramer, LP McKeown - The Journal of , 1990 - Am Soc Clin Investighttps://www.jci.org/articles/view/114896 Natural and hybrid ("Å\x93chimeric"Â\x9d) stable regulatory glyproline peptides IP Ashmarin, GE Samonina, LA Lyapina, AA Kamenskii - Pathophysiology, 2005 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0928468004001051 Inhibition of fibrinogen binding to GP IIb-IIIa by a GP IIIa peptide IF Charo, L Nannizzi, DR Phillips, MA Hsu - Journal of Biological , 1991 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0021925818523103 Discovery of an orally active non-peptide fibrinogen receptor antagonist based on the hydantoin scaffold HU Stilz, W Guba, B Jablonka, M Just - Journal of medicinal , 2001 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/jm001068s From a peptide lead to an orally active peptidomimetic fibrinogen receptor antagonist HU Stilz, W Guba, B Jablonka, M Just, O Klingler - Letters in Peptide , 1998 - Springerhttps://link.springer.com/article/10.1023/A:1008849013123 FRET-GP-A Local Measure of the Impact of Transmembrane Peptide on Lipids GCN Thakur , A Uday, P Jurkiewicz - Langmuir, 2023 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.langmuir.3c02505 Glyproline peptide family: review on bioactivity and possible origins G Samonina, I Ashmarin, L Lyapina - Pathophysiology, 2002 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0928468002000184 The disulfide-rich region of platelet glycoprotein (GP) IIIa contains hydrophilic peptide sequences that bind anti-GPIIIa autoantibodies from patients with immune DJS Beardsley, C Tang, BG Chen, C Lamborn - Biophysical , 2003 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S030146220300111X Peptide kinetics. Part 3.-Acid catalysed hydrolysis of glycyl-glycyl-phenylalanine DA Long, TG Truscott - Transactions of the Faraday Society, 1963 - pubs.rsc.orghttps://pubs.rsc.org/en/content/articlepdf/1963/tf/tf9635901833 Ca2+-dependent binding of a synthetic Arg-Gly-Asp (RGD) peptide to a single site on the purified platelet glycoprotein IIb-IIIa complex B Steiner, D Cousot, A Trzeciak, D Gillessen - Journal of Biological , 1989 - ASBMBhttps://www.jbc.org/article/S0021-9258(18)51601-X/abstract Efficiency of erythropoietin\s signal peptide for HIVMN-1 gp 120 expression AM Herrera, A Musacchio, JR Fernandez - Biochemical and , 2000 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0006291X00929747

Gly-Pro is a cyclic peptide that binds to DPP-IV and inhibits proteolytic activity. It has been shown to have inhibitory properties against infectious diseases and cancer tissues, as well as a fluorescence probe for the detection of DPP-IV. Gly-Pro is also a potential inhibitor of neuronal death and has been shown to have structural analysis in the form of molecular docking analysis.