15136-34-2_环二肽cyclo(Leu-Trp)_cyclo(Leu-Trp)(main chain cyclo)_cyclo(LW)(main chain cyclo)_200+种环二肽现货_ 现货多肽

环二肽cyclo(Leu-Trp)
Minamiura等人通过细菌蛋白酶从酪蛋白水解液中分离出二酮哌嗪环（Leu Trp）。它是奶酪中检测到的苦味化合物之一。

编号：132418

CAS号：15136-34-2

单字母：cyclo(LW)(main chain cyclo)

编号:	132418
中文名称:	环二肽cyclo(Leu-Trp)
中文同义词:	cyclo(Trp-Leu)(main chain cyclo)
英文名:	c(Leu-Trp)
英文同义词:	c(Trp-Leu)、cyclo(Trp-Leu)
CAS号:	15136-34-2
单字母:	cyclo(LW)(main chain cyclo)
三字母:	cyclo(Leu-Trp)(main chain cyclo)
氨基酸个数:	2
分子式:	C₁₇H₂₁N₃O₂
平均分子量:	299.37
精确分子量:	299.16
等电点(PI):	-
pH=7.0时的净电荷数:	0.97
平均亲水性:	-2.6
疏水性值:	1.45
外观与性状:	白色粉末状固体
消光系数:	5500
来源:	人工化学合成，仅限科学研究使用，不得用于人体。
纯度:	95%、98%
盐体系:	可选TFA、HAc、HCl或其它
生成周期:	2-3周
修饰类型:	酰胺键成环
储存条件:	负80℃至负20℃
标签:	200+种环二肽现货 现货多肽

The diketopiperazine cyclo(Leu-Trp) has been isolated by Minamiura et al. from casein hydrolyzate by bacterial proteinase. It is one of the bitter compounds detected in cheese.

Cyclo(-Leu-Trp) is a sweetener that has been used in the food industry for many years. Cyclo(-Leu-Trp) is able to bind with quinine and form a complex that can be detected using analytical methods. Cyclo(-Leu-Trp) has been investigated as a ligand that may be able to bind to receptors on cancer cells, which could lead to new treatments for cancer. Cyclo(-Leu-Trp) also has amphipathic properties and can form liposomes at high concentrations. This molecule has also been studied for its ability to induce transduction of DNA into bacterial cells and cellular thermogenesis.

环二肽又叫2,5-二酮哌嗪的衍生物,作为环肽成员中最小的一类环肽，专肽生物有部分环二肽的现货，也可以根据实验需求，定制含D型与L型，S与R构型的氨基酸。
T.Shiba et al., Biopolymers, 20, 1985 (1981)；http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=7306670
N.Minamiura et al., J. Biochem., 72, 841 (1972)；http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=4630112
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