Ac-WEHD-CHO, a very potent reversible inhibitor of caspase-1 (ICE). It bears the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM it belongs to the most potent reversible, peptide-based inhibitors described for any protease. For
编号：160342
CAS号：189275-71-6
单字母：Ac-WEHD-CHO
| 编号: | 160342 |
| 中文名称: | Caspase 1 Inhibitor VIII |
| 英文名: | Caspase 1 Inhibitor VIII |
| CAS号: | 189275-71-6 |
| 单字母: | Ac-WEHD-CHO |
| 三字母: | Ac N端乙酰化封端 -Trp色氨酸 -Glu谷氨酸 -His组氨酸 -Asp天冬氨酸 -CHOC端醛基化 |
| 氨基酸个数: | 4 |
| 分子式: | C28H33O9N7 |
| 平均分子量: | 611.6 |
| 精确分子量: | 611.23 |
| 等电点(PI): | 4 |
| pH=7.0时的净电荷数: | -1.76 |
| 平均亲水性: | 0.525 |
| 疏水性值: | -2.78 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | 5500 |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 醛肽 |
Ac-WEHD-CHO, a very potent reversible inhibitor of caspase-1 (ICE). It bears the optimal tetrapeptide recognition motif for this enzyme. With a Ki of 56 pM it belongs to the most potent reversible, peptide-based inhibitors described for any protease. For caspase-8 a Ki of 21.1 nM has been reported.
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