400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
D-(-)-2-Phenylglycine是脊髓中的一种抑制性神经递质，是NMDA受体的变构调节剂。用于制备半合成抗生素阿莫西林。
编号：115962
CAS号：875-74-1
单字母：
| 编号: | 115962 |
| 中文名称: | D-苯甘氨酸 |
| 英文名: | H-D-Phg-OH |
| CAS号: | 875-74-1 |
| 三字母: | |
| 沸点: | 288.7°Cat760mmHg |
| 熔点: | 302°C |
| 闪点: | 128.4°C |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 规格: | 1g,5g,25g,100g,1kg |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | D型氨基酸 |
| MDL号: | MFCD00008061 |
| 参考文献（References）: | <ALLPEPTIDE>Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.<ALLPEPTIDE>Aaron D Mills, et al. Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR. Bioorg Med Chem Lett. 2010 Jan 1;20(1):87-91.<ALLPEPTIDE>Antonella Caputo, et al. Mutation-specific potency and efficacy of cystic fibrosis transmembrane conductance regulator chloride channel potentiators. J Pharmacol Exp Ther. 2009 Sep;330(3):783-91.<ALLPEPTIDE>Choedchai Saehuan, et al. Isolation and characterization of a benzoylformate decarboxylase and a NAD+/NADP+-dependent benzaldehyde dehydrogenase involved in D-phenylglycine metabolism in Pseudomonas stutzeri ST-201. Biochim Biophys Acta. 2007 Nov;1770(11):1585-92.<ALLPEPTIDE>Hiroomi Nagata, et al. Structural scaffold of 18-crown-6 tetracarboxylic acid for optical resolution of chiral amino acid: X-ray crystal analyses and energy calculations of complexes of D- and L-isomers of tyrosine, isoleucine, methionine and phenylglycine. Org Biomol Chem. 2004 Dec 7;2(23):3470-5. |
| TPSA: | 63.32 |
| LogP : | 0.771 |
| H_Acceptors: | 2.0 |
| H_Donors: | 2.0 |
| Rotatable_Bonds: | 2.0 |
| 警示词: | Warning |
| 危险申明: | H302-H315-H319-H335 |
| 警告申明: | P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501 |
| GHS编码: | GHS07 |
| SMILES: | O=C(O)[C@H](N)C1=CC=CC=C1 |
D-(-)-2-Phenylglycine是脊髓中的一种抑制性神经递质，是NMDA受体的变构调节剂。用于制备半合成抗生素阿莫西林。
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