400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
| 编号: | 194305 |
| 中文名称: | Boc-βAla |
| 中文同义词: | Boc-β-丙氨酸 |
| 英文名: | Boc-β-Ala-OH |
| 英文同义词: | 3-tert-Butoxycarbonylaminopropionic acid |
| CAS号: | 3303-84-2 |
| 单字母: | Boc-βA-OH |
| 三字母: | Boc N端Boc保护；叔丁氧羰基或叔丁氧羰基（Boc）是胺的保护基团。Boc基团可用强酸去除，如用三氟乙酸在二氯甲烷中去除，或用HCl在甲醇中去除。 -βAlaβ-丙氨酸是天然存在的β氨基酸 -OHC端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。 |
| 氨基酸个数: | 1 |
| 分子式: | C8H15O4N1 |
| 平均分子量: | 189.21 |
| 精确分子量: | 189.1 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | - |
| 平均亲水性: | - |
| 疏水性值: | - |
| 沸点: | 333.9°Cat760mmHg |
| 熔点: | 76-78°C |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 规格: | 25g,100g |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | Boc保护氨基酸 丙氨酸类 |
| MDL号: | MFCD00037291 |
| 参考文献（References）: | <ALLPEPTIDE>Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1095. |
| TPSA: | 75.63 |
| LogP : | 0.9858 |
| H_Acceptors: | 3.0 |
| H_Donors: | 2.0 |
| Rotatable_Bonds: | 3.0 |
| 警示词: | Warning |
| 危险申明: | H302-H315-H319-H335 |
| 警告申明: | P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501 |
| GHS编码: | GHS07 |
| SMILES: | O=C(CCNC(OC(C)(C)C)=O)O |
Boc-ß-Ala-OH is an amino acid that inhibits the activity of gamma-aminobutyric acid (GABA) receptors. It has been shown to bind to the GABA receptor and block its activation by GABA. Boc-ß-Ala-OH is used as a building block for peptide synthesis, where it can be coupled with other amino acids to form a desired peptide sequence. This amino acid also possesses intramolecular hydrogen bonding interactions, which have been found to contribute to its inhibitory properties. Boc-ß-Ala-OH has a phase transition temperature of 104°C and is soluble in water below this point.
