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4 Ala ET-1, linear analog of ET-1 is a selective agonist for ET-B receptors.
编号:119815
CAS号:121204-87-3
单字母:H2N-ASASSLMDKEAVYFAHLDIIW-OH
| 溶解度: | Insoluble in water. Dissolve with small amount of DMSO. Then dilute with water or any desired buffer. |
[Ala1,3,11,15]-Endothelin (53-63) (TFA) 是一种内皮素 (ET)-1 的线性肽类似物,对内皮素 B (ETB) 受体具有高度选择性。
[Ala1,3,11,15]-Endothelin (53-63) (TFA), a linear peptide analog of endothelin (ET)-1, is a highly selective endothelin B (ETB) receptor[1].
人源丙氨酸 1、3、11、16 - 内皮素 - 1 包含多个丙氨酸取代,调节刚性与二级结构。该多肽用于解析受体相互作用的最小残基贡献。其简化侧链模式有助于主链驱动构象变化定位。研究者用于多肽工程与结构基序分析。
Ala1,3,11,16-Endothelin 1, human includes multiple alanine substitutions that modulate rigidity and secondary structure. The peptide is used to dissect minimal residue contributions to receptor interactions. Its simplified side-chain pattern aids in mapping backbone-driven conformational changes. Researchers employ it in peptide engineering and structural motif analysis.
Ala1·3·11·15)-Endothelin-1别名[Ala1,3,11,15] Endothelin-1, human,是ET-1的一个线性类似物,是ET-B受体一个选择性的激动剂。
| DOI | 名称 | |
|---|---|---|
| 10.1016/0006-291x(91)91367-l | [Ala1,3,11,15]endothelin-1 analogs with ETB agonistic activity | 下载 |
| 10.1016/s0006-291x(05)80123-8 | Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1,3,11,15]ET-1 | 下载 |





