血管紧张素 (1-12) 是局部生成血管紧张素的潜在前体。它在广泛的器官和组织中表达,包括小肠、脾脏、肝脏、肾脏和心脏。卡托普利和 CV-11974(一种血管紧张素 II I 型受体拮抗剂)可消除对静脉输注血管紧张素 (1-12) 的血管收缩和升压反应。
编号:112156
CAS号:914910-73-9
单字母:H2N-DRVYIHPFHLLY-OH
Angiotensin (1-12) represents a potential precursor for the local production of angiotensins. It is expressed in a wide range of organs and tissues including the small intestine, spleen, liver, kidneys, and heart. Vasoconstrictor and pressor response to intravenous infusion of angiotensin (1-12) are abolished by captopril and by CV-11974, an angiotensin II type I receptor antagonist.
DOI | 名称 | |
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10.1016/j.bbrc.2006.09.146 | Isolation and identification of proangiotensin-12, a possible component of the renin-angiotensin system | 下载 |
10.1152/ajpheart.00175.2008 | Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart | 下载 |
10.1152/ajpheart.91521.2007 | Localization of the novel angiotensin peptide, angiotensin-(1-12), in heart and kidney of hypertensive and normotensive rats | 下载 |