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| 溶解度: | Soluble in water |
甲状旁腺激素(44-68)(人)揭示参与稳定中间折叠状态的片段。带电残基有助于溶解度和动态灵活性。结构基序促进受体接触区域的作图。应用包括肽工程和激素信号传导研究中的功能分析。
Parathyroid Hormone (44-68), human, reveals a segment involved in stabilizing intermediate folding states. Charged residues assist in solubility and dynamic flexibility. Structural motifs facilitate mapping of receptor-contact regions. Applications include peptide engineering and functional analysis in hormone-signaling studies.
人甲状旁腺激素 (44-68) 跨越甲状旁腺激素的中央片段,对三级稳定至关重要。序列组成支持 β- 转角与螺旋加帽基序。构象行为揭示中部残基如何与 N 端信号结构域通讯。研究人员将其用于片段图谱与结构协同研究。
pTH (44-68) (human) spans a central segment of parathyroid hormone important for tertiary stabilization. Sequence composition supports β-turn and helix-capping motifs. Conformational behavior reveals how mid-region residues communicate with the N-terminal signaling domain. Researchers use it in fragment-mapping and structural cooperativity studies.
P.Gao et al., J. Bone Miner. Res., 16, 605(2001) : http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=11315988




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