400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
GLMVGGVVIA，β-淀粉样蛋白的部分序列，用于产生针对 Aβ 1-42 的抗体。李等人。研究了该片段和其他 Aβ 1-42 C 末端片段的聚集行为。
编号：118395
CAS号：178949-81-0
单字母：H2N-GLMVGGVVIA-OH
GLMVGGVVIA, a partial sequence of β-amyloid protein which is used for raising antibodies against Aβ 1-42. Li et al. studied the aggregation behavior of this and other Aβ 1-42 C-terminal fragments.
β-淀粉样蛋白（33-42）是淀粉样前体蛋白的一个片段，常因其在阿尔茨海默病中的作用而被研究。缩短的序列支持聚集行为和纤维形成的研究。它的特性使研究人员能够研究淀粉样斑块沉积的动力学和毒性。研究人员用它来探索神经退行性疾病和肽错误折叠的分子机制。
"β-Amyloid (33-42) is a fragment of the amyloid precursor protein, often studied for its role in Alzheimers disease. The shortened sequence supports investigation of aggregation behavior and fibril formation. Its properties allow researchers to examine the kinetics of amyloid plaque deposition and toxicity. Researchers use it to probe the molecular mechanisms underlying neurodegenerative diseases and peptide misfolding."
Amyloid β-Protein (33-42)别名Amyloid β/A4 Protein Precursor770 (704-713), APP770 (704-713), β-Amyloid (33-42)，是用来产生抗Aβ 1-42抗体的β-amyloid蛋白片段。
| DOI | 名称 | |
|---|---|---|
| 10.1523/JNEUROSCI.4391-04.2005 | Certain inhibitors of synthetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation | 下载 |
| 10.1021/bi902075h | Biophysical characterization of Abeta42 C-terminal fragments: inhibitors of Abeta42 neurotoxicity | 下载 |
| 10.1039/c3an36798c | Protein amyloids develop an intrinsic fluorescence signature during aggregation | 下载 |
| 10.1021/jacs.5b11012 | Proton Transfer and Structure-Specific Fluorescence in Hydrogen Bond-Rich Protein Structures | 下载 |
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