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| 编号: | 139457 |
| 中文名称: | Cbz-Gly-Pro |
| 中文同义词: | (S)-1-(2-(((苄氧基)羰基)氨基)乙酰基)吡咯烷-2-羧酸 |
| 英文名: | Z-Gly-Pro |
| 英文同义词: | (S)-1-(2-(((Benzyloxy)carbonyl)amino)acetyl)pyrrolidine-2-carboxylic acid |
| CAS号: | 1160-54-9 |
| 单字母: | Z-GP-OH |
| 三字母: | Cbz N端Cbz保护,苄氧羰基(Cbz,Z) -Gly甘氨酸:glycine。系统命名为 2-氨基乙酸。是编码氨基酸中没有旋光性的最简单的氨基酸,因具有甜味而得名。符号:G,Gly。 -ProL-脯氨酸:proline。系统命名为吡咯烷-(2S)-羧酸。为亚氨基酸。是编码氨基酸。在肽链中有特殊作用,如易形成顺式的肽键等。符号:P,Pro。 -OHC端羧基:C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时,通常将C端放在肽链的右边。 |
| 氨基酸个数: | 2 |
| 分子式: | C15H18O5N2 |
| 平均分子量: | 306.31 |
| 精确分子量: | 306.12 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | - |
| 平均亲水性: | - |
| 疏水性值: | -1 |
| 消光系数: | - |
| 来源: | 人工化学合成,仅限科学研究使用,不得用于人体。 |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | CBZ修饰肽 600+种二肽(Dipeptide)现货 |
| MDL号: | MFCD00037341 |
Cleavage product of the prolyl endopeptidase substrate Z- GLPGP.
Z-Gly-Pro is a synthetic peptide that has been shown to inhibit proteolytic enzymes. It binds to the active site of the enzyme and blocks its activity. The peptide has also been shown to have locomotor activity, as it stimulates stem cell factor and cell factor production in vitro. Z-Gly-Pro has also been shown to be an inhibitor binding molecule that can bind with other molecules such as inhibitors of proteases and tyrosine kinase receptors. This inhibition may help regulate physiological functions such as locomotion, proliferation, and differentiation of cells.
| DOI | 名称 | |
|---|---|---|
| 10.1074/jbc.M207386200 | Substrate-dependent competency of the catalytic triad of prolyl oligopeptidase | 下载 |





