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三甘氨酸，三肽氨基肽酶的底物。

Triglycine, substrate for tripeptide aminopeptidase.

"Peptide H-GGG-OH is a Research Peptide with significant interest within the field academic and medical research. Recent citations using H-GGG-OH include the following: Humidity-responsive self-assembly of short peptides with super-flexibility Z Zhu, J Yang , H Zhao, Y Wu, T Bai, H Zhang, Y Song - , 2024 - pubs.rsc.orghttps://pubs.rsc.org/en/content/articlehtml/2024/ce/d4ce00031e Investigation on Non-Covalent Complexes of Cyclodextrins with GGG and GFF Tripeptides in Gas Phase by Mass Spectrometry X He, C Xu, Y Chu, C Ding - Acta Chimica Sinica, 2013 - sioc-journal.cnhttp://sioc-journal.cn/Jwk_hxxb/EN/10.6023/A12110904 Zwitterionic stationary phase with covalently bonded phosphorylcholine type polymer grafts and its applicability to separation of peptides in the hydrophilic interaction W Jiang , G Fischer, Y Girmay, K Irgum - Journal of Chromatography a, 2006 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0021967306011095 Free energies and equilibria of peptide bond hydrolysis and formation RB Martin - Biopolymers: Original Research on Biomolecules, 1998 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/(SICI)1097-0282(19980415)45:5%3C351::AID-BIP3%3E3.0.CO;2-K Exploring the sequence space for (tri-) peptide self-assembly to design and discover new hydrogels PWJM Frederix , GG Scott, YM Abul-Haija - Nature , 2015 - nature.comhttps://www.nature.com/articles/nchem.2122 Local effect of glycine substitution in a model helical peptide PC Lyu , PC Wang , MI Liff - Journal of the American , 1991 - ACS Publicationshttps://pubs.acs.org/doi/pdf/10.1021/ja00009a052 Vibrational signatures of sodiated oligopeptides (GG-Na+, GGG-Na+, AA-Na+ and AAA-Na+) in the gas phase OP Balaj, C Kapota, J Lemaire - International Journal of , 2008 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1387380607004125 Dissociation of the peptide bond in protonated peptides MJ Polce, D Ren , C Wesdemiotis - Journal of Mass , 2000 - Wiley Online Libraryhttps://analyticalsciencejournals.onlinelibrary.wiley.com/doi/abs/10.1002/1096-9888(200012)35:12%3C1391::AID-JMS85%3E3.0.CO;2-1 Nuclear Magnetic Resonance Study of the Protolysis Kinetics of the Peptide Hydrogens of Triglycine1a M Sheinblatt - Journal of the American Chemical Society, 1966 - ACS Publicationshttps://pubs.acs.org/doi/pdf/10.1021/ja00962a007 Triglycine (GGG) Adopts a Polyproline II (pPII) Conformation in Its Hydrated Crystal Form: Revealing the Role of Water in Peptide Crystallization M Guo , I Rosbottom , L Zhou, CW Yong - The Journal of , 2021 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/acs.jpclett.1c01622 Characterization of the Zn (II) binding properties of the human Wilms tumor suppressor protein C-terminal zinc finger peptide KL Chan, I Bakman, AR Marts, Y Batir - Inorganic , 2014 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ic500862b Catalytic peptide hydrolysis by mineral surface: Implications for prebiotic chemistry K Marshall-Bowman , S Ohara, DA Sverjensky - et Cosmochimica Acta, 2010 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S0016703710003984 Reactions of allyl isothiocyanate with alanine, glycine, and several peptides in model systems K Cejpek, J ValuÅ¡ek, J VelacaÂ\xadÅ¡ek - Journal of agricultural and food , 2000 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/jf991019s In Vitro and in Vivo Evaluation of 64Cu-Labeled DOTAâË\x86â\x80\x99LinkerâË\x86â\x80\x99Bombesin(7âË\x86â\x80\x9914) Analogues Containing Different Amino Acid Linker Moieties JJ Parry, TS Kelly, R Andrews - Bioconjugate , 2007 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/bc0603788 Separation of tripeptides in binary mixtures using ion-exchange membrane adsorber J Labanda , J Llorens - Separation and Purification Technology, 2023 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1383586623002812 Refining the model for selective cleavage at acidic residues in arginine-containing protonated peptides G Tsaprailis, acaÂ\x81 Somogyi , EN Nikolaev - International Journal of , 2000 - Elsevierhttps://www.sciencedirect.com/science/article/pii/S1387380699002213 Ion-Binding Study by 17O Solid-State NMR Spectroscopy in the Model Peptide Gly-Gly-Gly at 19.6 T EY Chekmenev , KW Waddell, J Hu, Z Gan - Journal of the , 2006 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja060191r Copper-mediated peptide radical ions in the gas phase E Bagheri-Majdi, Y Ke, G Orlova, IK Chu - The Journal of , 2004 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/jp049531q Proton migration and tautomerism in protonated triglycine CF Rodriquez, A Cunje, T Shoeib , IK Chu - Journal of the , 2001 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/ja0015904 Solid-state IR-LD spectroscopic and theoretical analysis of glycine-containing peptides and their hydrochlorides BB Ivanova, T Kolev , SY Zareva - : Original Research on , 2006 - Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/abs/10.1002/bip.20512 Thermodynamics and Reaction Mechanisms for Decomposition of a Simple Protonated Tripeptide, H+GGA: From H+GGG to H+GAG to H+GGA A Mookherjee , PB Armentrout - Journal of the American Society for , 2022 - ACS Publicationshttps://pubs.acs.org/doi/abs/10.1021/jasms.1c00345 125I labeled mesenchymal-epithelial transition factor binding peptide-Gly-Gly-Gly.125I-cMBP-GGG A Chopra - Molecular Imaging and Contrast agent Database , 2004 - europepmc.orghttps://europepmc.org/books/n/micad/cmbpggg125i/?extid=23077755&src=med Mesenchymal-epithelial transition factor binding peptide-Gly-Gly-Gly-conjugated to Cy5. 5 cMBP-GGG-Cy5. 5 A Chopra - Molecular Imaging and Contrast agent Database , 2004 - europepmc.orghttps://europepmc.org/books/n/micad/cmbpgggcy55/"

Gly-Gly-Gly is a fluorescent probe that has been shown to be cytotoxic, with a 1:1 ratio of glycolic acid and glyoxylic acid. Gly-Gly-Gly is an ester hydrochloride that can be used as a fluorescence probe in electrochemical impedance spectroscopy. It has been shown to have biological properties and to be structurally similar to the group P2 polymerase chain reaction (PCR) primer. Gly-Gly-Gly is able to inhibit the polymerase chain reaction by binding to the template DNA strands, inhibiting the formation of the hydrogen bonds required for DNA replication. This inhibition leads to strand breakage, preventing duplication of genetic material.