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ALM-488一种新型静脉注射荧光素缀合肽,可结合神经相关结缔组织,在活体小鼠和人类离体神经组织中的实时荧光成像 (FL) 下标记周围神经
编号:637554
CAS号:2276787-79-0
单字母:5FAM-QVPWEEPYYVVKKSSGG-CONH2
Bevonescein (ALM-488) 是一种新型静脉注射荧光素缀合肽,可结合神经相关结缔组织,在活体小鼠和人类离体神经组织中的实时荧光成像 (FL) 下标记周围神经。Bevonescein 是一种肽连接示踪剂,可荧光标记完整和退化的神经。
体内研究:
Bevonescein (ALM-488;900 nmol;静脉给药;90 分钟的观察期) 通过体内实时荧光成像 (FL) 发现可以改善雌性小鼠 (SKH-1 无毛、野生型、~25 克) 完整神经、退化神经和部分再生神经的神经识别。
FAM标记说明:
Carboxyfluorescein (FAM) is fluorophor with an excitation at 492 nm ▉ and emission of 517 nm ▉. Donors like FAM and 5FAM are often paired together with acceptors (CPQ2) for FRET experiments.

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