短杆菌肽 A 是短杆菌肽的肽成分，短杆菌肽是一种最初从短杆菌中分离的抗生素混合物。
编号：200496
CAS号：11029-61-1
单字母：For-VGAlAvVvWlWlWlW-NHCH2CH2OH
Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α).
Gramicidin A is a peptide component of gramicidin, an antibiotic mixture originally isolated from B. brevis. Gramicidin A is a highly hydrophobic channel-forming ionophore that forms channels in model membranes that are permeable to monovalent cations. Gramicidin A induces degradation of hypoxia inducible factor 1 α (HIF-1α).
很多蛋白在细胞中非常容易被降解，或被标记，进而被选择性地破坏。但含有部分D型氨基酸的多肽则显示了很强的抵抗蛋白酶降解能力。
| DOI | 名称 | |
|---|---|---|
| 10.1021/la026717c | Cholesterol-Modulated Lipid−Peptide Communication in Fluid Bilayers | 下载 |
