用于测定尿激酶活性的底物。它也被凝血酶、纤溶酶和胰蛋白酶以及补体成分 C3/C5 转化酶切割。也称为 GK 肽,用于研究蛋白质糖化和美拉德产物的形成。
编号:200012
CAS号:14752-92-2
单字母:Ac-GK-OMe
编号: | 200012 |
中文名称: | 二肽Ac-Gly-Lys-甲酯化 |
CAS号: | 14752-92-2 |
单字母: | Ac-GK-OMe |
三字母: | Ac N端乙酰化封端 -Gly甘氨酸 -Lys赖氨酸 -OMeC端甲酯化修饰 |
氨基酸个数: | 2 |
分子式: | C11H21O4N3 |
平均分子量: | 259.3 |
精确分子量: | 259.15 |
等电点(PI): | - |
pH=7.0时的净电荷数: | 1 |
平均亲水性: | 3 |
疏水性值: | -2.15 |
消光系数: | - |
来源: | 人工化学合成,仅限科学研究使用,不得用于人体。 |
储存条件: | 负80℃至负20℃ |
标签: | 二肽(Dipeptide) |
Substrate for the determination of urokinase activity. It is also cleaved by thrombin, plasmin and trypsin as well as complement component C3/C5 convertases. Also known as GK-peptide, used in studies on protein glycation and formation of Maillard products.
DOI | 名称 | |
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10.1016/0006-291x(82)92119-2 | Tyrosyl residues of two molecular forms of human urinary urokinase: their ionization mode characterized by spectrophotometric and CD titrations and reactivity with cyanuric fluoride in relation to enzymic activity | 下载 |
10.1093/oxfordjournals.jbchem.a133453 | A comparative study of high molecular weight urokinase and low molecular weight urokinase | 下载 |
10.1074/jbc.271.32.19338 | Protein cross-linking by the Maillard reaction. Isolation, characterization, and in vivo detection of a lysine-lysine cross-link derived from methylglyoxal | 下载 |
10.1021/acs.chemrestox.6b00141 | Molecular Structures of Isolevuglandin-Protein Cross-Links | 下载 |