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专注多肽 服务科研

| 编号: | 128717 |
| 中文名称: | 二肽-2、Dipeptide-2 |
| 英文名: | Dipeptide-2 |
| CAS号: | 24587-37-9 |
| 单字母: | H2N-VW-OH |
| 三字母: | H2N N端氨基:N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时,通常将N端放在肽链的左边。 -ValL-缬氨酸:valine。系统命名为(2S)-氨基-3-甲基丁酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号:V,Val。在某些放线菌素如缬霉素中存在 D-缬氨酸。 -TrpL-色氨酸:tryptophan[e]。系统命名为(2S)-氨基-3-(3-吲哚基)丙酸。是编码氨基酸,哺乳动物的必需氨基酸。符号:W,Trp。某些抗菌素中含有 D-色氨酸。 -OHC端羧基:C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时,通常将C端放在肽链的右边。 |
| 氨基酸个数: | 2 |
| 分子式: | C16H21N3O3 |
| 平均分子量: | 303.36 |
| 精确分子量: | 303.16 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 0.97 |
| 平均亲水性: | -2.45 |
| 疏水性值: | 1.65 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | 5500 |
| 来源: | 人工化学合成,仅限科学研究使用,不得用于人体。 |
| 纯度: | 95%、98% |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 600+种二肽(Dipeptide)现货 |
The dipeptide Val-Trp is a potent, competitive dipeptide angiotensin I-converting enzyme inhibitor with a Ki of 0.3 µM. Dipeptide-2 is a component of various cosmetic formulations, e.g. for anti-wrinkle and anti-aging cosmetics.

H-Val-Trp-OH is a noncompetitive inhibitor of the enzyme tyrosinase, which plays a role in melanin production. It also has radical scavenging activities and can inhibit the activity of other enzymes such as glucose 6-phosphate dehydrogenase and acetylcholinesterase. The compound is stable in aqueous solution and can be used to study the effects of H-Val-Trp-OH on wheat germ cells. It is composed of an amino acid sequence that resembles tyrosine, with a carboxylate group attached to the hydroxyl group at position 3. H-Val-Trp-OH is most active against tyrosinase when it is in its activated form, but it can also act as an inhibitor when it is not activated. The compound inhibits the activity of tyrosinase by binding to its active site and blocking the binding or catalysis of substrate molecules. This inhibition occurs through competitive interactions with
| DOI | 名称 | |
|---|---|---|
| 10.1002/1096-9888(200006)35:6<683::AID-JMS994>3.0.CO;2-D | Reaction competition in the fragmentation of protonated dipeptides | 下载 |
| 10.1021/jf0350865 | Inhibitory profile of nonapeptide derived from porcine troponin C against angiotensin I-converting enzyme | 下载 |
| 10.1111/j.1750-3841.2009.01138.x | Isolation and identification of antihypertensive peptides from antarctic krill tail meat hydrolysate | 下载 |
| 10.1016/j.peptides.2012.07.030 | Tryptophan-containing milk protein-derived dipeptides inhibit xanthine oxidase | 下载 |
| 10.1016/j.foodchem.2016.12.039 | Identification and quantification of ACE-inhibiting peptides in enzymatic hydrolysates of plant proteins | 下载 |
| 10.1016/j.foodchem.2014.06.059 | Tryptophan-containing dipeptides are C-domain selective inhibitors of angiotensin converting enzyme | 下载 |





