400-998-5282
专注多肽 服务科研

| 编号: | 194118 |
| 中文名称: | 二肽Pro-Arg、prolylarginine |
| 英文名: | Pro-Arg、prolylarginine |
| CAS号: | 2418-74-8 |
| 单字母: | H2N-PR-OH |
| 三字母: | H2N N端氨基:N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时,通常将N端放在肽链的左边。 -ProL-脯氨酸:proline。系统命名为吡咯烷-(2S)-羧酸。为亚氨基酸。是编码氨基酸。在肽链中有特殊作用,如易形成顺式的肽键等。符号:P,Pro。 -ArgL-精氨酸:arginine。系统命名为(2S)-氨基-5-胍基戊酸。在生理条件下带正电荷,为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号:R,Arg。 -OHC端羧基:C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时,通常将C端放在肽链的右边。 |
| 氨基酸个数: | 2 |
| 分子式: | C11H21N5O3 |
| 平均分子量: | 271.32 |
| 精确分子量: | 271.16 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 1.97 |
| 平均亲水性: | 3 |
| 疏水性值: | -3.05 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | - |
| 来源: | 人工化学合成,仅限科学研究使用,不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 600+种二肽(Dipeptide)现货 |
PR inhibited angiotensin-1 converting enzyme (ACE), IC₅₀ 4.1 μM.
"H-Pro-Arg-OH acetate salt is a synthetic, antioxidative molecule that has been shown to lower blood pressure in animals. It is also an effective inhibitor of the oxidation of diploid cells and has been shown to be safe for long-term use. H-Pro-Arg-OH acetate salt is used as a structural probe for studies on the binding of fibrinogen to plasminogen. This compound has also been shown to reduce protamines ability to inhibit fibrinolysis, which may lead to improved blood clotting times."
H-Pro-Arg-OH是一个序列为PR的二肽,它可以抑制血管紧张素转化酶(ACE)的活性,IC50=4.1 μM。
| DOI | 名称 | |
|---|---|---|
| 10.1271/bbb.100893 | Human bitter taste receptors hTAS2R8 and hTAS2R39 with differential functions to recognize bitter peptides | 下载 |
| 10.1021/jf2041593 | Discovery of salt taste enhancing arginyl dipeptides in protein digests and fermented fish sauces by means of a sensomics approach | 下载 |
| 10.1016/j.aca.2013.08.004 | Application of cinchona-sulfonate-based chiral zwitterionic ion exchangers for the separation of proline-containing dipeptide rotamers and determination of on-column isomerization parameters from dynamic elution profiles | 下载 |
| 10.1021/acs.jafc.6b02716 | Salt Taste Enhancing l-Arginyl Dipeptides from Casein and Lysozyme Released by Peptidases of Basidiomycota | 下载 |
| 10.1271/bbb.58.1767 | Structure and activity of angiotensin I converting enzyme inhibitory peptides from sake and sake lees | 下载 |
| 10.1002/1097-0231(20000930)14:18<1654::AID-RCM76>3.0.CO;2-R | Grazing incidence surface-induced dissociation of protonated peptides generated by matrix-assisted laser desorption/ionization | 下载 |





