24587-41-5_二肽Phe-Trp_H2N-Phe-Trp-OH_H2N-FW-OH_600+种二肽(Dipeptide)现货

二肽Phe-Trp
它是一种高效的ACE抑制剂。

编号：197976

CAS号：24587-41-5

单字母：H2N-FW-OH

编号:	197976
中文名称:	二肽Phe-Trp
中文同义词:	L-苯丙氨酰基-L-色氨酸
英文名:	Phe-Trp
英文同义词:	Phenylalanyltryptophan; L-phenylalanyl-L-tryptophan; Phe-Trp; FW dipeptide; Phenylalanine Tryptophan dipeptide
CAS号:	24587-41-5
单字母:	H2N-FW-OH
三字母:	H2N N端氨基：N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时，通常将N端放在肽链的左边。 -Phe L-苯丙氨酸：phenylalanine。系统命名为(2S)-氨基-3-苯基丙酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：F，Phe。 -Trp L-色氨酸：tryptophan[e]。系统命名为(2S)-氨基-3-(3-吲哚基)丙酸。是编码氨基酸，哺乳动物的必需氨基酸。符号：W，Trp。某些抗菌素中含有 D-色氨酸。 -OH C端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。
氨基酸个数:	2
分子式:	C₂₀H₂₁N₃O₃
平均分子量:	351.4
精确分子量:	351.16
等电点(PI):	-
pH=7.0时的净电荷数:	0.97
平均亲水性:	-2.95
疏水性值:	0.95
外观与性状:	白色粉末状固体
沸点:	688.3±55.0°Cat760mmHg
消光系数:	5500
来源:	人工化学合成，仅限科学研究使用，不得用于人体。
纯度:	95%、98%
盐体系:	可选TFA、HAc、HCl或其它
生成周期:	2-3周
储存条件:	负80℃至负20℃
标签:	600+种二肽(Dipeptide)现货

MDL号:	MFCD00083788
参考文献（References）:	<ALLPEPTIDE>V Rizzo, et al. Co-oligopeptides of aromatic amino acids and glycine with a variable distance between the aromatic residues. VI. Circular dichroism studies of Co-oligopeptides of l-phenylalanine, L-tryptophan, and glycine. Biopolymers. 1977 Feb;16(2):449-60.
TPSA:	108.21
LogP :	1.8498
H_Acceptors:	3.0
H_Donors:	4.0
Rotatable_Bonds:	7.0
警示词:	Warning
危险申明:	H302-H315-H319-H335
警告申明:	P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
GHS编码:	GHS07
SMILES:	O=C(O)[C@H](CC1=CNC2=C1C=CC=C2)NC([C@H](CC3=CC=CC=C3)N)=O

它是一种高效的ACE抑制剂。

It is a highly potent ACE inhibitor.

H-Phe-Trp-OH is an inhibitor of protein phosphatase 2A and is used in the diagnosis of kidney cancer. Magnetic resonance spectroscopy (MRS) is a technique that can be used to measure the concentration of phosphate groups in tissues. Hypophosphatemia, or low phosphate levels in the body, is associated with a number of diseases, including kidney cancer. This molecule inhibits the activity of phosphatase 2A and can be used as a diagnostic marker for such conditions. The enzyme has been shown to have an inhibitory effect on vitamin D3-induced synthesis of calcitriol (1,25-dihydroxyvitamin D3), which may be due to its ability to sequester phosphate groups. H-Phe-Trp-OH binds to proteins and has been shown to have an inhibitory effect on other enzymes such as histidine phosphatase and glutamine phosphatase.

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