400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
| 编号: | 123704 |
| 中文名称: | Fmoc-Phe-OH、Fmoc-L-苯丙氨酸 |
| 英文名: | Fmoc-Phe-OH |
| CAS号: | 35661-40-6 |
| 单字母: | Fmoc-F-OH |
| 三字母: | Fmoc N端Fmoc保护，9-芴甲氧羰基（Fmoc）是伯胺和仲胺的保护基团。在固相肽合成（SPPS）中，它是氨基酸主链的常用保护基，因为它可以很容易地用哌啶去除，而不会干扰树脂和肽之间的酸不稳定连接体。 -PheL-苯丙氨酸：phenylalanine。系统命名为(2S)-氨基-3-苯基丙酸。是编码氨基酸。是哺乳动物的必需氨基酸。符号：F，Phe。 -OHC端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。 |
| 氨基酸个数: | 1 |
| 分子式: | C24H21O4N1 |
| 平均分子量: | 387.43 |
| 精确分子量: | 387.15 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | - |
| 平均亲水性: | -2.5 |
| 疏水性值: | 2.8 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | Fmoc保护氨基酸 苯丙氨酸类 |
Fmoc固相多肽合成中Fmoc保护的苯丙氨酸Phe
Fmoc-Phe-OH is a natural compound that has been shown to have antimicrobial properties. The biological properties of Fmoc-Phe-OH are not well understood, but it has been shown to have anticancer effects in some cases and to inhibit axonal growth when combined with the protein laminin. Fmoc-Phe-OH can be synthesized by the reaction of pheine with trifluoroacetic acid followed by treatment with h9c2 cells. The analytical method for determining the concentration of Fmoc-Phe-OH is based on intramolecular hydrogen exchange between hydrogen atoms on the amide group and hydrogens on neighboring methylene groups. This process releases heat, which is detected by a thermometer.\nEND>
