这种在血浆和尿液中发现的二肽是在谷胱甘肽分解代谢过程中产生的。半胱氨酰甘氨酸已被建议诱导氧化应激和脂质过氧化，导致人类癌症的发展。
编号：181988
CAS号：19246-18-5
单字母：H2N-CG-OH
| 编号: | 181988 |
| 中文名称: | 二肽Cys-Gly |
| 英文名: | Cys-Gly |
| CAS号: | 19246-18-5 |
| 单字母: | H2N-CG-OH |
| 三字母: | H2N N端氨基：N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时，通常将N端放在肽链的左边。 -Cys半胱氨酸：cysteine。L-半胱氨酸的系统命名为(2R)-氨基-3-巯基丙酸，是编码氨基酸。符号：C，Cys。D-半胱氨酸存在于萤火虫的萤光素酶中。 -Gly甘氨酸：glycine。系统命名为 2-氨基乙酸。是编码氨基酸中没有旋光性的最简单的氨基酸，因具有甜味而得名。符号：G，Gly。 -OHC端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。 |
| 氨基酸个数: | 2 |
| 分子式: | C5H10N2O3S1 |
| 平均分子量: | 178.21 |
| 精确分子量: | 178.04 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 1.94 |
| 平均亲水性: | -1 |
| 疏水性值: | 1.05 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 二肽(Dipeptide) |
This dipeptide found in plasma and urine is generated during the catabolism of glutathione. Cysteinylglycine has been suggested to induce oxidative stress and lipid peroxidation, leading to the development of human cancers.
| DOI | 名称 | |
|---|---|---|
| 10.1016/0003-2697(92)90456-h | Determination of the in vivo redox status of cysteine, cysteinylglycine, homocysteine, and glutathione in human plasma | 下载 |
| 10.1007/s00216-006-0454-x | Analysis of urine for cysteine, cysteinylglycine, and homocysteine by high-performance liquid chromatography | 下载 |
| 10.1007/s00726-007-0590-4 | High-throughput capillary electrophoresis method for plasma cysteinylglycine measurement: evidences for a clinical application | 下载 |
| 10.1158/0008-5472.CAN-07-3061 | Plasma cysteinylglycine levels and breast cancer risk in women | 下载 |
| 10.1271/bbb.70395 | Structural analysis of the fundamental polymer of the sheath constructed by Sphaerotilus natans | 下载 |
| 10.1016/j.jasms.2010.01.027 | Mobile protons versus mobile radicals: gas-phase unimolecular chemistry of radical cations of cysteine-containing peptides | 下载 |
| 10.1021/tx300045f | Hydrogen exchange equilibria in thiols | 下载 |
| 10.1111/mmi.12274 | Molecular and structural basis of glutathione import in Gram-positive bacteria via GshT and the cystine ABC importer TcyBC of Streptococcus mutans | 下载 |
| 10.3390/molecules19079552 | Formation of a flavin-linked peptide | 下载 |
| 10.1039/c5an00206k | Complementing reversed-phase selectivity with porous graphitized carbon to increase the metabolome coverage in an on-line two-dimensional LC-MS setup for metabolomics | 下载 |
| 10.1039/c5an01629k | An integrated metabolomics workflow for the quantification of sulfur pathway intermediates employing thiol protection with N-ethyl maleimide and hydrophilic interaction liquid chromatography tandem mass spectrometry | 下载 |
| 10.1002/anie.201506019 | Radical Formation in the Gas-Phase Ozonolysis of Deprotonated Cysteine | 下载 |
| 10.1074/jbc.M115.700989 | Peptide Bond Synthesis by a Mechanism Involving an Enzymatic Reaction and a Subsequent Chemical Reaction | 下载 |
| 10.1016/j.jmr.2016.10.003 | Robust conversion of singlet spin order in coupled spin-1/2 pairs by adiabatically ramped RF-fields | 下载 |
| 编号 | 名称 | CAS号 |
| 197625 | 二肽Ac-Ala-Lys-NH2 | |
| Ac-AK-CONH2 | ||
