400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
对应于物质 P 的 N 端序列的二肽。 在 SP 代谢过程中，H-Arg-Pro-OH 和 H-Lys-Pro-OH 被后脯氨酸二肽基氨肽酶 (PPDAP) 分裂，这是一种在大脑中表达的酶,.
编号：131126
CAS号：2418-69-1
单字母：H2N-RP-OH
| 编号: | 131126 |
| 中文名称: | 二肽Arg-Pro |
| 英文名: | Arg-Pro |
| CAS号: | 2418-69-1 |
| 单字母: | H2N-RP-OH |
| 三字母: | H2N N端氨基：N-terminal amino group。在肽或多肽链中含有游离a-氨基的氨基酸一端。在表示氨基酸序列时，通常将N端放在肽链的左边。 -ArgL-精氨酸：arginine。系统命名为(2S)-氨基-5-胍基戊酸。在生理条件下带正电荷，为编码氨基酸。是幼小哺乳动物的必需氨基酸。符号：R，Arg。 -ProL-脯氨酸：proline。系统命名为吡咯烷-(2S)-羧酸。为亚氨基酸。是编码氨基酸。在肽链中有特殊作用，如易形成顺式的肽键等。符号：P，Pro。 -OHC端羧基：C-terminal carboxyl group。在肽或多肽链中含有游离羧基的氨基酸一端。在表示氨基酸序列时，通常将C端放在肽链的右边。 |
| 氨基酸个数: | 2 |
| 分子式: | C11H21N5O3 |
| 平均分子量: | 271.32 |
| 精确分子量: | 271.16 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 1.97 |
| 平均亲水性: | 3 |
| 疏水性值: | -3.05 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 600+种二肽(Dipeptide)现货 |
Dipeptide corresponding to the N-terminal sequence of substance P. During SP metabolism, H-Arg-Pro-OH and H-Lys-Pro-OH are split off by post-proline dipeptidyl aminopeptidase (PPDAP), an enzyme expressed in the brain.
H-Arg-Pro-OH sulfate salt is a synthetic peptide that binds to the receptor for filtrates. It is used to treat skin conditions such as dermatitis, eczema, and psoriasis. H-Arg-Pro-OH sulfate salt has been shown to be effective in inhibiting clostridium from producing proteins. This drug also inhibits the uptake of these proteins by blocking the binding of phosphorylated lysine residues to their receptors on the cell membrane. It has been shown to hydrolyze amide bonds and can be used as a catalyst for bond cleavage reactions.
| DOI | 名称 | |
|---|---|---|
| 10.1016/j.foodchem.2012.02.183 | Production of dipeptidyl peptidase IV inhibitory peptides from defatted rice bran | 下载 |
| 10.1016/j.jasms.2005.02.008 | Stereoselective discrimination and quantification of arginine and N-blocked arginine enantiomers by formation and dissociation of calcium-mediated diastereomeric trimer complexes with a chiral reference compound using electrospray ionization-ion trap tandem mass spectrometry | 下载 |
| 10.1021/jf2041593 | Discovery of salt taste enhancing arginyl dipeptides in protein digests and fermented fish sauces by means of a sensomics approach | 下载 |
| 10.1371/journal.pone.0070055 | Characterization of the recombinant exopeptidases PepX and PepN from Lactobacillus helveticus ATCC 12046 important for food protein hydrolysis | 下载 |
| 10.1016/j.aca.2013.08.004 | Application of cinchona-sulfonate-based chiral zwitterionic ion exchangers for the separation of proline-containing dipeptide rotamers and determination of on-column isomerization parameters from dynamic elution profiles | 下载 |
| 10.1007/s13361-013-0762-2 | 157 nm photodissociation of dipeptide ions containing N-terminal arginine | 下载 |
| 10.1111/j.1432-1033.1986.tb09401.x | Post-proline dipeptidyl-aminopeptidase from synaptosomal membranes of guinea-pig brain. A possible role for this activity in the hydrolysis of His-ProNH2, arising from the action of synaptosomal membrane pyroglutamate aminopeptidase on thyroliberin | 下载 |
| 10.1111/j.1471-4159.1980.tb11186.x | Separation of two dipeptidyl aminopeptidases in the human brain | 下载 |
