二肽 H-Ala-Gln-OH 和 H-Gly-Gln-OH 是细胞培养基中 Gln 的稳定替代品，与 Gln 相比，它们耐受高压灭菌并释放出较少量的不需要的氨。Ala-Gln 和 Gly-Gln 也已发现用作胃肠外营养中的 Gln 来源。
编号：132803
CAS号：39537-23-0
单字母：H2N-AQ-OH
| 编号: | 132803 |
| 中文名称: | 二肽Ala-Gln |
| 英文名: | Ala-Gln |
| CAS号: | 39537-23-0 |
| 单字母: | H2N-AQ-OH |
| 三字母: | H2N N端氨基 -Ala丙氨酸 -Gln谷氨酰胺 -OHC端羧基 |
| 氨基酸个数: | 2 |
| 分子式: | C8H15N3O4 |
| 平均分子量: | 217.22 |
| 精确分子量: | 217.11 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 0.97 |
| 平均亲水性: | -0.15 |
| 疏水性值: | -0.85 |
| 外观与性状: | 白色粉末状固体 |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 二肽(Dipeptide) 食品研究与营养 |
The dipeptides H-Ala-Gln-OH and H-Gly-Gln-OH are stable substitutes for Gln in cell culture media, which tolerate autoclaving and liberate a lower amount of undesired ammonia than Gln. Ala-Gln and Gly-Gln have also found use as Gln sources in parenteral nutrition.
| DOI | 名称 | |
|---|---|---|
| 10.1016/j.chroma.2012.01.020 | Quantitative high-performance liquid chromatography-tandem mass spectrometry impurity profiling methods for the analysis of parenteral infusion solutions for amino acid supplementation containing L-alanyl-L-glutamine | 下载 |
| 10.1177/0148607108317880 | Efficacy of parenteral nutrition supplemented with glutamine dipeptide to decrease hospital infections in critically ill surgical patients | 下载 |
| 10.1177/014860719001400417 | Glutamine-containing dipeptides in parenteral nutrition | 下载 |
| 10.1007/BF02623607 | Influence of two glutamine-containing dipeptides on growth of mammalian cells | 下载 |
| 10.1016/s0928-0987(98)00012-8 | Degradation kinetics of L-alanyl-L-glutamine and its derivatives in aqueous solution | 下载 |
| 10.1021/jp0561625 | Conformational analysis of XA and AX dipeptides in water by electronic circular dichroism and 1H NMR spectroscopy | 下载 |
