400-998-5282
专注多肽 服务科研
400-998-5282
专注多肽 服务科研
Cyclo(Gly-Pro) has been detected in rat brain. In the passive avoidance test in rats, synthetic cycloprolylglycine showed 76% antiamnesic activity.
编号：154212
CAS号：3705-27-9/19179-12-5
单字母：cyclo(GP)(main chain cyclo)
| 编号: | 154212 |
| 中文名称: | 环二肽cyclo(Gly-Pro) |
| 中文同义词: | cyclo(Pro-Gly) |
| 英文名: | c(Gly-Pro) |
| 英文同义词: | c(Pro-Gly)、cyclo(Pro-Gly) |
| CAS号: | 3705-27-9/19179-12-5 |
| 单字母: | cyclo(GP)(main chain cyclo) |
| 三字母: | cyclo(Gly-Pro)(main chain cyclo) |
| 氨基酸个数: | 2 |
| 分子式: | C7H10N2O2 |
| 平均分子量: | 154.17 |
| 精确分子量: | 154.07 |
| 等电点(PI): | - |
| pH=7.0时的净电荷数: | 0.97 |
| 平均亲水性: | - |
| 疏水性值: | -1 |
| 外观与性状: | 白色粉末状固体 |
| 沸点: | 447.9°Cat760mmHg |
| 消光系数: | - |
| 来源: | 人工化学合成，仅限科学研究使用，不得用于人体。 |
| 纯度: | 95%、98% |
| 盐体系: | 可选TFA、HAc、HCl或其它 |
| 生成周期: | 2-3周 |
| 修饰类型: | 酰胺键成环 |
| 储存条件: | 负80℃至负20℃ |
| 标签: | 200+种环二肽现货 现货多肽 |
| MDL号: | MFCD01083707 |
| 参考文献（References）: | <ALLPEPTIDE>Fumitaka Hayasaka, et al. Production Method for Cyclic Dipeptide Derived from Native Collagen. Food Science and Technology Research, 22 (4), 477-483, 2016.<ALLPEPTIDE>T A Gudasheva, et al. Identification of a Novel Endogenous Memory Facilitating Cyclic Dipeptide Cyclo-Prolylglycine in Rat Brain. FEBS Lett. 1996 Aug 5;391(1-2):149-52.<ALLPEPTIDE>Ying-ying Sun, et al. Isolation, Purification, and Identification of Antialgal Substances in Green Alga Ulva Prolifera for Antialgal Activity Against the Common Harmful Red Tide Microalgae. Environ Sci Pollut Res Int. 2016 Jan;23(2):1449-59. |
| TPSA: | 49.41 |
| LogP : | -0.8928 |
| H_Acceptors: | 2.0 |
| H_Donors: | 1.0 |
| Rotatable_Bonds: | 0.0 |
| 警示词: | Warning |
| 危险申明: | H302-H317 |
| 警告申明: | P261-P264-P270-P272-P280-P302+P352-P330-P362+P364-P501 |
| GHS编码: | GHS07 |
| SMILES: | O=C(NC1)C(CCC2)N2C1=O |
Cyclo(Gly-Pro) has been detected in rat brain. In the passive avoidance test in rats, synthetic cycloprolylglycine showed 76% antiamnesic activity.
环二肽又叫2,5-二酮哌嗪的衍生物,作为环肽成员中最小的一类环肽，专肽生物有部分环二肽的现货，也可以根据实验需求，定制含D型与L型，S与R构型的氨基酸。
A.Trigos et al., Nat. Prod. Lett., 8, 199 (1996)
T.A.Gudasheva et al., FEBS Lett., 391, 149 (1996)；http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=8706904
