应江苏省分子医学生物技术重点实验室的邀请，美国国立卫生研究院国家癌症研究所的江永平博士来我校访问，并做学术报告。

报告题目：Prevention and Treatment of Cancer with Our Own Immune System

报告人：江永平 博士 （美国国立卫生研究院国家癌症研究所）

时间：2012年11月16日 下午3：00

地点：生命科学学院三楼多功能报告厅

报告人简历：江永平，男，博士。1984年在南京师范大学获得学士学位，1987年在中国科学院动物研究所（北京）获得动物学硕士学位，1996年在University of Nebraska Medical Center获得生物化学和分子生物学博士学位。

学术兼职：

·        Steering committee member for NCI fellows and young investigators, 2002 - 2005

·        Steering committee member of Chinese NIH Immunology Interest Club, 2002 – present

·        Manager of Chinese NIH Immunology Interest Club, 2003-2004, 2010 - present

·        Member of the American Association of Immunologists, 2000 – 2004

·        Member of the NIH Immunology Interest Group, 1997 – 2003

部分代表性论文：

·         Chiang* YJ and Hodes RJ   2011   Cbl enforces Vav1 dependence and a restricted pathway of T cell development.    PLoS ONE 6(4): e18542  (*Corresponding author)

·         Martiniova L, J. Lu, J. Chiang, M. Bernardo, R. Lonser, Z. Zhuang, K. Pacak     2011   Pharmacologic Modulation of Serine/Threonine Phosphorylation Highly Sensitizes PHEO in a MPC Cell and Mouse Model to Conventional Chemotherapy.  PLoS ONE 6: e14678

·         Lu J, Chiang J, Iyer RR, Thompson E, Kaneski CR, Xu DS, Yang C, Chen M, Hodes RJ, Lonser RR, Brady RO, Zhuang Z  2010    Decreased glucocerebrosidase activity in Gaucher disease parallels quantitative enzyme loss due to abnormal interaction with TCP1 and c-Cbl.  PNAS 107: 21665-70

·         Chiang* YJ, Calado RT, HathcockKS, Lansdorp PM, Young NS and Hodes RJ   2010  Telomere length is inherited with resetting of the telomere set-point.  PNAS 107: 10148. (*Corresponding author)

·         Jang IK., Zhang J., Chiang YJ, Kole, H., Cronshaw DG, Zou Y. and Gu, H.   2010   Grb2 Functions at the Top of the TCR-induced Tyrosine Kinase Cascade to Control Thymic Selection. PNAS 107: 10620-25. 

·         Wen J, Chiang*, YJ, Gao C, Xue H, Xu J, Ning Y, Hodes RJ, Gao X, Chen YG.   2010   Loss of Dact1 disrupts planar cell polarity signaling by altering dishevelled activity and leads to posterior malformation in mice. J. Biological Chemistry 285: 11023-30  (*Co-first author)

·         Lu J, Kovach JS, Johnson F, Chiang J, Hodes R, Lonser R, Zhuang Z.  2009 Inhibition of serine/threonine phosphatase PP2A enhances cancer chemotherapy by blocking DNA damage induced defense mechanisms.  PNAS 106:14734

·         Scharner D, Rössig L, Carmona G, Chavakis E, Urbich C, Fischer A, Kang TB, Wallach D, Chiang YJ, Deribe YL, Dikic I, Zeiher AM, Dimmeler S    2009  Caspase-8 Is Involved in Neovascularization-Promoting Progenitor Cell Functions.   Aterioscler Thromb Vasc Biol 29: 571-578

·         Chiang*, Y.J., M. S. Jordan, R. Horai, P. L. Schwartzberg, G. A. Koretzky, and R. J. Hodes   2009  Cbl Enforces an SLP76-dependent Signaling Pathway for T Cell Differentiation. J. Biological Chemistry 284: 4429-4438   (*Corresponding author)

·         Nakamura, A., J.Y. Chiang, K.S. Hathcock, I. Horikawa, O.A. Sedelnikova, R.J. Hodes and W.M. Bonner  2008  Both telomeric and non-telomeric DNA damage are determinants of mammalian cellular senescence. Epigenetics & Chromatin 1: 6

·         Chiang*, Y. J., S. J. Hsiao, D. Yver, S.W. Cushman,  Lino Tessarollo, Susan Smith and R. J. Hodes  2008   Tankyrase 1 and tankyrase 2 are essential but redundant for mouse embryonic development.  PLoS ONE 3: e2639  (*Corresponding author)

·         Chiang, Y. J., I.K. Jang, R. J. Hodes and H. Gu   2007   Ablation of Cbl-b provides protection against inoculated and spontaneous tumors. J. Clinical Investigation 117: 1029-36

·         Cheng, A., K. Shin-ya, T. Miura, S.-C. Tang, R. Wan, H. Tang, R. Khatri, M. Gleichman, X. Ouyang, D. Liu, H.-R. Park , J. Y. Chiang, and M. P. Mattson   2007  Telomere Protection Mechanisms Change During Neurogenesis and Neuronal Maturation:  Newly Generated Neurons are Hypersensitive to Telomere and DNA Damage.  J. Neuroscience 24: 3722-33

·        H. Song, L. Zhang, Y. J. Chiang, R. Siraganian, R. J. Hodes  2007  Redundancy in B cell developmental pathways: c-Cbl inactivation rescues early B cell development through a BLNK-independent pathway. J. Immunology 178: 926-35